Host Qwen2.5 72B Instruct on RunPod
Qwen2.5 72B Instruct needs 1x 80GB+ GPU, and RunPod's current cheapest qualifying row is A100 PCIE at $1.39/hr.
RunPod rows that can host Qwen2.5 72B Instruct
The cheapest tracked way to host Qwen2.5 72B Instruct on RunPod is A100 PCIE at $1.39/hr. The overall tracked market floor is $1.00/hr on Vast.ai, so RunPod is $0.39/hr above the current floor.
| GPU | VRAM | Per GPU | Estimated hourly | Estimated monthly | Updated |
|---|---|---|---|---|---|
| A100 PCIE | 80GB | $1.39/hr | $1.39/hr | $1,015/mo | Jun 21, 2026 |
| A100 SXM4 | 80GB | $1.49/hr | $1.49/hr | $1,088/mo | Jun 21, 2026 |
| H100 PCIE | 80GB | $2.89/hr | $2.89/hr | $2,110/mo | Jun 21, 2026 |
| H100 NVL | 94GB | $3.19/hr | $3.19/hr | $2,329/mo | Jun 21, 2026 |
| H100 SXM | 80GB | $3.29/hr | $3.29/hr | $2,402/mo | Jun 21, 2026 |
| H200 | 141GB | $4.39/hr | $4.39/hr | $3,205/mo | Jun 21, 2026 |
| B200 | 192GB | $5.89/hr | $5.89/hr | $4,300/mo | Jun 21, 2026 |
Why this setup does or does not fit
1x 80GB+ GPU
1x 80GB GPU minimum; 2x 80GB for healthier serving margins. Long prompts, batching, and KV cache can require extra headroom.
Premium multilingual
Premium open-weight quality with wide language coverage, but it firmly lives in 80GB-class infrastructure.
Qwen 72B
Best suited to teams that want premium open-weight quality with wide language coverage.
Qwen2.5 72B Instruct on RunPod FAQ
Can I host Qwen2.5 72B Instruct on RunPod?
The cheapest tracked way to host Qwen2.5 72B Instruct on RunPod is A100 PCIE at $1.39/hr.
What GPU memory does Qwen2.5 72B Instruct need?
Our baseline for Qwen2.5 72B Instruct is 1x 80GB+ GPU. The practical recommendation is 1x 80GB GPU minimum; 2x 80GB for healthier serving margins.
Is RunPod the cheapest provider for Qwen2.5 72B Instruct?
The overall tracked market floor is $1.00/hr on Vast.ai, so RunPod is $0.39/hr above the current floor.
How fresh is this RunPod Qwen2.5 72B Instruct cost page?
This page recalculates from the latest tracked on-demand rows. The freshest qualifying RunPod row shown here is from Jun 21, 2026.