Host Qwen2.5 72B Instruct on AWS
Qwen2.5 72B Instruct needs 1x 80GB+ GPU, and AWS's current cheapest qualifying row is A100 SXM4 at $3.09/hr.
AWS rows that can host Qwen2.5 72B Instruct
The cheapest tracked way to host Qwen2.5 72B Instruct on AWS is A100 SXM4 at $3.09/hr. The overall tracked market floor is $1.00/hr on Vast.ai, so AWS is $2.09/hr above the current floor.
Why this setup does or does not fit
1x 80GB+ GPU
1x 80GB GPU minimum; 2x 80GB for healthier serving margins. Long prompts, batching, and KV cache can require extra headroom.
Premium multilingual
Premium open-weight quality with wide language coverage, but it firmly lives in 80GB-class infrastructure.
Qwen 72B
Best suited to teams that want premium open-weight quality with wide language coverage.
Qwen2.5 72B Instruct on AWS FAQ
Can I host Qwen2.5 72B Instruct on AWS?
The cheapest tracked way to host Qwen2.5 72B Instruct on AWS is A100 SXM4 at $3.09/hr.
What GPU memory does Qwen2.5 72B Instruct need?
Our baseline for Qwen2.5 72B Instruct is 1x 80GB+ GPU. The practical recommendation is 1x 80GB GPU minimum; 2x 80GB for healthier serving margins.
Is AWS the cheapest provider for Qwen2.5 72B Instruct?
The overall tracked market floor is $1.00/hr on Vast.ai, so AWS is $2.09/hr above the current floor.
How fresh is this AWS Qwen2.5 72B Instruct cost page?
This page recalculates from the latest tracked on-demand rows. The freshest qualifying AWS row shown here is from Jun 21, 2026.